Endocrine Abstracts

Objective: We will analyze various characteristics of the patients who attend the HUMV Diabetic Foot Unit for a week. The variables studied are sex, age, type of diabetes, years of evolution, type of current treatment, last glycosylated hemoglobin, presence of other cardiovascular risk factors and existence of previous ulcerations and amputationsMaterial and Methods: We worked with Microsoft Excel to coollect the data and perform the statistical study.</...

Issues: In developing nations diagnosis of diabetes brings mental-trauma/depression in family. Focused treatment for pediatric age-group is unavailable in developing-countries. 26% of diagnosed diabetics are children’s. Adequately trained physicians/Nurses in issues of pediatric-diabetes provide continuity of care, relief from depression and smooth transition from diagnosis to treatment. Qualitative collaborative relationship between these makes diabetics life bearable. O...

S Hillier, University of Edinburgh, Edinburgh, United Kingdom AbstractSteve Hillier is Professor of Reproductive Endocrinology at the University of Edinburgh, where he has directed infertility laboratory services at the Royal Infirmary of Edinburgh and undertaken research at the Centre for Reproductive Biology for over 20 years. Previously (1982–1985), working with Robert (now Lord) Winston, he established the <i...

The testis provides stem cell niches which are populated by spermatogonial stem cells. The seminiferous epithelium is the exclusive site where germline cells are proliferating and entering meiosis in the adult organism. The existence of stem cells offers clinically relevant options for preservation and restoration of male fertility. New approaches based on male germ cell transplantation and testicular tissue grafting can be applied to generate sperm. Germ cell transplantation ...

An audit examining self-management skills and pre hospital management of adrenal crisis. This audit was performed following a clinical incident involving an Addison’s patient who suffered and survived a cardiac arrest as a direct result of an adrenal crisis. The patient involved in the initial incident lived close to a major A&E.The paramedic arm of the audit came about after consideration of the geographical nature of this locality. Even if the...

Issues: Newer anti-diabetic therapies out of reach of >84% populations of Asia. Pharmaceuticals donot provide price discounts in resource-constrained-countries. incidence of insulin resistance neglected issue in resource-poor nations. Diabetes forums failed to address this concern. Hence we formed liaison study group of four clinics to analyse this issue and make policy paper. Resource poor nations have little technical expertise/manpower to study insulin resistance. Lack ...

A systematic survey of low S-cortisol levels at the department of clinical chemistry: indications for testing and frequency of undiagnosed adrenal insufficiency.Background: S-cortisol is frequently analyzed at clinical chemistry departments. Low levels of S-cortisol needs to be promptly acted on if the cause is undiagnosed adrenal insufficiency (AI). The causes of S-cortisol testing are however multiple and low levels are necessarily not alarming if foun...

During the past several years the wide application of sensitive brain imaging techniques (CT, MRI) has led to an increasing recognition of asymptomatic lesions in the pituitary. Although their etiology covers a wide range of pathologies, most incidentally discovered pituitary lesions are benign adenomas, ranging in size from micro- (<10 mm) to macro- (>10 mm) adenomas. Micro-incidentalomas are very common, with a reported incidence in normal individuals of 4–20%. ...

Cyclooxygenase (COX), the rate-limiting enzyme in prostaglandin (PG) biosynthesis exists in two isoforms, COX-1 and COX-2. They are encoded by two separate genes, and show cell-type specific expression and regulation. The expression of COX-1 is constitutive, whereas that of COX-2 is inducible by cytokines/growth factors or inflammatory stimuli. Since the processes of ovulation and implantation are considered analogous to 'proinflammatory' responses, and the involvement of PGs ...

Lipodystrophy including familial, acquired and secondary forms displays the full spectrum of the metabolic syndrome including severe insulin resistance, hyperinsulinaemia; hypertension, hypertriglyceridaemia, low HDL cholesterol, and hyperglycaemia1. This group have an absolute or partial reduction in fat mass, yet often show more extreme metabolic features than obese individuals.Partial lipodystrophy may be genetic or acquired. Genetic causes...